Open Genomic Surveillance

Welcome to ARGUS

One family. Seven ESKAPE pathogens. One accession-first workflow.

An open, serverless genomic surveillance platform for the WHO priority ESKAPE pathogens. No installation. No login. No API key. Just filter, verify, and export your accession list.

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The bottleneck

Finding the right genomes should not be this hard.

The exponential growth of publicly available pathogen genomes has created an unprecedented opportunity for genomic epidemiology. Yet a persistent bottleneck remains: retrieving a defined subset of genomes that match specific genotypic or epidemiological criteria.

Old way Hours of scripting before science

  • Download static compressed TSVs from five different sources
  • Manually join tables by accession — mismatch errors guaranteed
  • Write Python scripts to filter genotype and metadata separately
  • Debug the pipeline when a column name changes
  • Query again from scratch for each new criterion
  • Duplicate data across tools and pipelines

ARGUS way Minutes from query to accession list

  • Open one interactive browser page — no install, no login
  • Stack filters across genotype, geography, and metadata in one query
  • Watch matching counts update live as you narrow the search
  • Export a clean plain-text accession list with one click
  • Feed directly into NCBI Datasets for genome retrieval
  • Every annotation, every metadata field — one architecture
The solution

Four steps from query to genome.

Every ARGUS platform is built around the same workflow — the actual downstream deliverable, a clean accession list, sits at the centre of the interface.

1

Filter

Stack filters across genotype, geography, and metadata. Sequence type, resistance gene, country, source, year — all in one place.

2

Verify

See live counts, distribution charts, and lineage context before you download anything. Confirm the query returns what you need.

3

Export

One click downloads a plain-text accession list. No scripting. No API keys. No CSV wrangling. Just one ID per line.

4

Download

Feed the list to NCBI Datasets and retrieve the underlying assemblies. Every platform is designed around this final step.

The family

Seven ESKAPE pathogens. One architecture.

Each platform is a species-specific resource with its own name, its own DOI, its own release cycle, and its own community of users — but they all share the same accession-first, serverless, metadata-integrated foundation.

🦖
SAURUS
Staphylococcus aureus
Typing, gene retrieval, and metadata for public S. aureus genomes.
🌑
ECLIPSE
Escherichia coli
MLST, phylogroups, serotypes, and CHTyper for public E. coli genomes.
🌊
ABYSS
Acinetobacter baumannii
Pasteur MLST, IC1–IC12, KL/OCL capsules, OXA-51, and carbapenemase tracking.
🏆
KLEOS
Klebsiella pneumoniae
Pasteur ST, wzi capsular typing, carbapenemases, and hypervirulence markers.
💧
PSEUDA
Pseudomonas aeruginosa
MLST, O-antigen typing, intrinsic resistance, and T3SS virulence effectors.
👑
EMPIRE
Enterococcus faecium
MLST, vanA/vanB typing, and surface protein epidemiology for VRE.
🌀
ENTROPY
Enterobacter spp.
Species-level ST typing, AmpC variants, and carbapenemase tracking.

📚 Please cite the platforms you use

Each platform carries its own citation block on its landing page and its own Zenodo DOI on release. Full citation lists for every platform are on the Resources page.